Amniotic membrane transplantation combined with anterior chamber washout and topical corticosteroids yielded favorable results in the treatment of severe peripheral ulcerative keratitis with membranous endothelial exudation, according to a study. The prospective study included 12 eyes of 12 patients with peripheral ulcerative keratitis. Mean patient age was 58.3 years. Ulcers were identified at the corneal periphery and were accompanied by central corneal epithelial defects and stromal edema. Anterior segment optical coherence tomography was used to observe membranous endothelial exudates. Mean duration of ulcers before treatment was 3 months.