Insignificant link found between genotype, response to AREDS supplements

Genotype had an insignificant association with response to nutritional supplementation, according to study findings.In a retrospective analysis of data from the first AREDS, researchers attempted to gauge whether genotypes at two major loci related to age-related macular degeneration — complement factor H (CFH) and age-related maculopathy susceptibility 2 (ARMS2) — had any significant effect on the relative benefits of AREDS supplements in a subset of patients at high risk for progression to late AMD.

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