Month: August 2014

Topical cyclosporine A effective therapy before, following refractive surgery

Topical cyclosporine A was found to be an effective therapy for optimizing patients prior to refractive surgery, as well as for the treatment of new-onset or worsened dry eye following surgery, according to researchers.Researchers retrospectively analyzed 1,056 patients who were screened for refractive surgery during a 5-year period to assess levels of pre- and postoperative dry eye, as well as patients’ responsiveness to topical cyclosporine A treatment.

Triple therapy outperforms double therapy in treatment of PCV

Triple therapy comprising photodynamic therapy, intravitreal bevacizumab and subtenon triamcinolone acetonide injections markedly improved vision in eyes with treatment-naïve subfoveal polypoidal choroidal vasculopathy, according to study findings.The retrospective, comparative, interventional case series included 36 eyes of 36 patients with treatment-naïve subfoveal polypoidal choroidal vasculopathy. Seventeen patients underwent PDT combined with intravitreal Avastin (bevacizumab, Genentech), and 19 patients underwent PDT, intravitreal bevacizumab and subtenon triamcinolone acetonide (STTA) injections. All patients underwent slit lamp biomicroscopy, fundus imaging, fluorescein angiography and optical coherence tomography.

Genetics company receives $1.4 million NIH grant

The NIH has granted a total of $1,367,504 to 23andMe, a personal genetic testing company, for a 2-year project to enhance the company’s online database and research engine. The project will make access to aggregate, summary data available to outside researchers. Catherine Afarian, spokesperson for 23andMe, told HemOnc Today the company wants “the best and brightest minds in the world to have access” to their data. By granting access to outside experts, research that may have taken years to complete can be conducted quickly in real-time.

How do surgeons approach enhancements in refractive surgery patients?

CEDARS Debates is a monthly feature in Ocular Surgery News. CEDARS — Cornea, External Disease, and Refractive Surgery Society — is a group of cornea, cataract and refractive surgery specialists, here to discuss some of the latest hot topics in ophthalmology.As laser refractive surgery enters its third decade of widespread use in the U.S., an increasing number of patients are now returning for enhancements. LASIK patients, in particular, present the dilemma of how to approach the enhancement.

Canaloplasty poses risk of Descemet’s membrane detachment

Canaloplasty was associated with a slight risk of Descemet’s membrane detachment, with or without intracorneal hemorrhage, according to study findings.The retrospective study included 162 eyes of 115 patients who underwent canaloplasty. Researchers evaluated visual acuity, IOP, number of glaucoma medications and incidence of Descemet’s membrane detachment (DMD) for up to 1 year.

Advances in imaging technologies improve screening, detection of diabetic eye disease

For years, the main reason for ophthalmic screening in patients with diabetes has been to detect the presence of diabetic retinopathy or diabetic macular edema — both of which may lead to blindness if untreated — relying on either a dilated fundus examination or color photography.One expert estimated that a dilated fundus examination performed by an ophthalmologist detects diabetic retinopathy in more than 90% of cases. Even so, subtle diabetic macular edema may not be picked up without an optical coherence tomography examination, according to David M. Brown, MD, FACS, (Read more...)