Oral acyclovir may be used to prevent recurrence of herpes simplex keratitis

LAS VEGAS — Recurrence of herpes simplex keratitis is commonly associated with corneal scarring and poor corneal graft survival. Early diagnosis and treatment helps prevent permanent corneal scarring caused by the virus’ lytic reaction and its immune-mediated response, according to a speaker here. Daily applications of trifluridine 1% solution or ganciclovir 0.15% are commonly used to treat acute herpetic epithelial keratitis and have been shown to shorten the clinical course, Natalie Afshari, MD, said here at Cornea Subspecialty Day preceding the American Academy of Ophthalmology annual meeting.

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