Glucose metabolism affects macular thickness in diabetic patients

SEATTLE — Pericentral macular thickness decreased in diabetic patients with worsening glucose metabolism, which may reflect early neurodegenerative changes, according to a poster presented here. “Macular thinning may be an early sign of diabetic retinopathy and macular thickening may be a sign of diabetic macular edema,” Eline E. De Clerck, MD, and colleagues said in the poster at the Association for Research in Vision and Ophthalmology meeting. “We therefore evaluated to what extent macular thickness differed between individuals with prediabetes and individuals with type 2 diabetes with or without cysts compared with individuals with a normal glucose metabolism.”