Several risk factors associated with ophthalmologic findings in infants with presumed Zika virus

Infants presumed to have the Zika virus who had smaller cephalic perimeters at birth and whose mothers reported virus symptoms in the first trimester of pregnancy were more likely to have fundus abnormalities, according to a study. Researchers tested the cerebrospinal fluid of 24 of 40 infants with microcephaly for the Zika virus (ZIKV) in a cross-sectional study conducted in Brazil; all 24 were found to have positive results for ZIKV infection. Fourteen of 22 infants with ophthalmoscopic findings and 10 of 18 infants without ophthalmoscopic findings were positive for the virus.