TREX-AMD study shows relationship of risk factors to macular atrophy

SAN FRANCISCO — Subfoveal choroidal thickness and subretinal hyperreflective material thickness were risk factors statistically significantly related to macular atrophy in eyes with neovascular age-related macular degeneration, according to a study.“But in eyes that had no macular atrophy at baseline, the presence of [subretinal hyperreflective material], the thickness of SHRM and the thickness of the [pigment epithelium detachment], and the presence of hemorrhage at baseline on color fundus photographs were all significant predictors of the new development, or the new occurrence, of atrophy along the 18 months of follow-up,” Nizar Abdelfattah, MD, said at the American Society of Retina Specialists annual meeting.