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Publication Exclusive: Surgeons detail steps for simple limbal epithelial transplantation
In 1964, Jose Barraquer described a surgical technique for limbal stem cell deficiency, or LSCD. The paramount finding of extensive LSCD is conjunctival transgression across the corneal-conjunctival border and the limbus and onto the cornea, resulting in vascularization, chronic inflammation, persistent epithelial defects and recurrent erosions, which uninterrupted can progress to corneal opacity and transform to a skin-like corneal surface with corneal blindness. These border “policemen” between the corneal and conjunctival territories are largely accepted as the limbal stem cells that are believed to be housed within the radial fibrovascular (Read more...)