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Oral re-esterified omega-3 fatty acids improve tear osmolarity, dry eye symptoms
Tear osmolarity, omega-3 index levels, ocular surface disease index symptom scores, tear break-up time and matrix metalloproteinase-9 improved in patients with dry eye disease who consumed re-esterified omega-3 fatty acids, according to a study. The multicenter, prospective, interventional, placebo-controlled, double-masked study included 54 patients randomized to receive four soft gels of 1,680 mg of eicosapentaenoic acid/560 mg of docosahexaenoic acid, and 51 patients who received 3,136 mg of linoleic acid, the control supplement. Patients took the supplements daily for 12 weeks.