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Publication Exclusive: Taking a closer look at persistent hyperplastic primary vitreous
Persistent hyperplastic primary vitreous, or PHPV, is a form of persistent fetal vasculature, first described by Reese in 1955. The exact etiology of PHPV remains unknown, but it characteristically presents as unilateral leukocoria. PHPV is divided into subtypes: anterior, posterior and combined. In anterior PHPV, the remnant vascular stalk is seen attached to the posterior surface of the lens capsule, but it does not extend back to the optic nerve. Posterior PHPV occurs when the remnant vascular stalk is seen arising off the optic nerve but does not reach the (Read more...)