Combination of squalamine, ranibizumab improves BCVA in eyes with retinal vein occlusion

Patients with macular edema secondary to retinal vein occlusion who received a combination of squalamine and ranibizumab had a better improvement in best corrected visual acuity than patients who received ranibizumab alone, according to a study. The single-center, open-label, randomized trial included 20 eyes of 20 consecutive patients; nine eyes had nonischemic central retinal vein occlusion, eight eyes had branch retinal vein occlusion, and three eyes had hemicentral retinal vein occlusion.

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