US, UK trials underway to compare treatments for CRVO

KOLOA, Hawaii — Not long ago, there were no effective treatments for central retinal vein occlusion; now there are multiple treatments, Michael S. Ip, MD, said at Retina 2017, where he updated colleagues on the SCORE2 and LEAVO trials.Both are comparative effectiveness research trials looking at the relative safety and efficacy of anti-VEGF drugs and corticosteroids for central retinal vein occlusion. SCORE2 is a U.S. trial, and LEAVO is sponsored by the National Health Service in the U.K.