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Frequent anti-VEGF injections may be associated with increased risk of glaucoma surgery
A large pharmacoepidemiologic study carried out in British Columbia found that seven or more intravitreal injections of bevacizumab are associated with an increased risk of glaucoma surgery.Using population-based Ministry of Health-supported databases, data analysis was performed on a cohort of patients who had received intravitreal Avastin (bevacizumab, Genentech) injections for age-related macular degeneration between January 2009 and December 2013, focusing on the cases that subsequently underwent glaucoma surgery. For each of these cases, 10 controls matched by age, pre-existing glaucoma, number of injections per year and duration of follow-up were (Read more...)