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Regression time shorter with ophthalmic artery chemosurgery plus intravitreous chemotherapy
Ophthalmic artery chemosurgery with intravitreous chemotherapy to treat class 3 retinoblastoma vitreous seeds resulted in a shorter time to regression compared with ophthalmic artery chemosurgery alone, according to a retrospective study.Researchers at Memorial Sloan-Kettering Cancer Center included 40 eyes containing clouds (class 3 vitreous seeds) of 40 retinoblastoma patients; 19 were treated with ophthalmic artery chemosurgery (OAC) and 21 were treated with OAC plus intravitreous and periocular chemotherapy. Time to regression of seeds, ocular survival and disease-free survival were the main outcome measures.