The use of a cryopreserved amniotic membrane in dry eye disease correlated with corneal nerve regeneration as evidenced by a significant increase in corneal nerve density and corneal sensitivity, according to a study presented at the American Academy of Ophthalmology meeting.
The prospective, controlled study compared self-retained cryopreserved amniotic membrane (Prokera Slim, Bio-Tissue) vs. conventional treatment in patients with moderate to severe dry eye disease.
Twenty subjects were equally randomized to receive Prokera Slim or conventional maximum treatment. The maximal conventional
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