Adding lidocaine to subconjunctival cefazolin in pars plana vitrectomy, with or without phacoemulsification, yielded no analgesic benefit, according to a study.
The randomized, single-masked clinical trial evaluated 54 patients who were naïve to ophthalmic surgery and required retinal surgery at Toronto Western Hospital. Subjects were randomly assigned to receive a subconjunctival injection of either 0.3 mL cefazolin and 0.2 mL balanced salt solution or 0.3 mL cefazolin and 0.2 mL lidocaine 2% at the end of retinal surgery.
Subjects were later asked to rate their pain at the beginning of
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