Corneal endothelium tolerates acute IOP increase after bevacizumab injection

Short-term effects of rapid IOP spikes on corneal endothelium were “tolerable” after intravitreal bevacizumab injection, according to a study.
Researchers prospectively evaluated the effects on corneal endothelium of acute increase in IOP following intravitreal injection of 2.5 mg/0.1 mL Avastin (bevacizumab, Genentech) in 42 patients with central serous chorioretinopathy or diabetic macular edema. Each patient’s contralateral eye, which had no history of intravitreal injection, was used as control.
Mean IOP at baseline before the injection was 11.48 mm Hg. Mean IOP increased

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