Hydroxychloroquine has been used in American medicine since 1955. It is primarily prescribed to treat chloroquine-sensitive malaria, rheumatoid arthritis, lupus erythematosus, porphyria cutanea tarda and post-Lyme disease arthritis. It is an anti-inflammatory that interferes with toll-like receptors, especially toll-like receptor 9, reducing the activation of plasmacytoid dendritic cells.
Typical doses are in the range of 200 mg to 400 mg per day, and the medicine is conveniently taken by mouth. Like all medicines with potential side effects, the lowest effective dose is preferred, and many
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