The first patient has been enrolled in the phase 3 TRANQUILITY trial evaluating reproxalap for the treatment of patients with dry eye disease, according to a press release from Aldeyra Therapeutics.
The multicenter randomized, double-masked, parallel-design, vehicle-controlled clinical trial is designed to assess the safety and efficacy of reproxalap ophthalmic solution 0.25% vs. vehicle based on objective sign endpoints of dry eye. The analysis will include tear reactive aldehyde species (RASP) levels, Schirmer test and conjunctival redness. Results from a run-in cohort of 20 patients are
Uncategorized