Submandibular gland transplantation showed efficacy for the treatment of end-stage refractory dry eye disease, while transplantation of minor salivary glands may be effective in treating less severe dry eye, according to a study.
The retrospective clinical cohort study included 73 eyes with refractory dry eye disease (DED) divided into three groups: group A, which included 35 eyes with end-stage DED treated with submandibular gland (SMG) transplantation; group B, which included 20 eyes with end-stage DED treated with minor salivary glands (MSGs) transplantation; and group C, which included 18