Autofluorescence shows two pathways to geographic atrophy

Geographic atrophy could involve two separate disease pathways, one with soft drusen and one with subretinal drusenoid deposits, according to a study published in Eye.
R. Theodore Smith, MD, PhD, and colleagues were able to differentiate these markers in patients using quantitative autofluorescence (qAF).
“We found it was consistently twice as bright in the patients with SDDs as those with drusen when they reached advanced AMD and came from a unique diseased layer,” Smith, lead author of the study, said in a Mount Sinai press release. “Combined with our prior (Read more...)

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