SEATTLE — Based on the amount of retinal tissue preserved, pegcetacoplan saves 5,000 to 9,000 retinal pigment epithelium cells over a period of 2.5 years and up to 15,000 in extrafoveal lesions, according to a study presented here.
“And, as we know, each RPE cell protects a lot of photoreceptors,” Sunir J. Garg, MD, FACS, FASRS, said at the American Society of Retina Specialists annual meeting.
Geographic atrophy is a relentlessly progressive disease, and it progresses by about 1 mm2 every 6 months, he said. The DERBY, OAKS and GALE studies showed efficacy of pegcetacoplan