A research letter published in JAMA Ophthalmology described the case of a patient with geographic atrophy who reported multiple small floaters after intravitreal injection of pegcetacoplan.
The patient was seen 2 weeks after injection but said that the floaters were present from the first day after the treatment. Clinical examination revealed multiple syringe-related silicone oil droplets, showing as hyperechogenic areas on B-scan ultrasonography.
According to the authors, the problem may originate from the act of filling the syringe according to the label instructions for pegcetacoplan, which