Intraoperative floppy iris syndrome is a clinical situation encountered during phacoemulsification characterized by loss of iris muscle tone, predominantly seen in patients on alpha-1 receptor antagonist medication.
The floppiness of the iris tissue along with constant billowing into the corneal incision is a surgical challenge.
The iris tissue in intraoperative floppy iris syndrome (IFIS) behaves differently compared with a normal iris. As the dexterity of the iris tissue is lost, it tends to remain updrawn toward the corneal incision or side-port incision. The corneal wound acts as a pressure