Transepithelial corneal cross-linking with supplemental oxygen achieved comparable corneal stromal demarcation line depth to that of conventional epi-off CXL and had a similar safety profile in a study.
“Added advantages were faster recovery and improved patient comfort,” Lim Li, MD, said at the European Society of Cataract and Refractive Surgeons meeting.
Typically, epi-on CXL shows a shallower demarcation line as compared with epi-off CXL, indicating insufficient UV light penetration and efficacy of the procedure. In the literature, a 60% rate of keratoconus progression was