A genetic association study using two-sample Mendelian randomization analysis was able to demonstrate a shared genetic basis and an association between myopic refractive error and the risk for primary open-angle glaucoma.
Observation analyses were conducted to evaluate the association between mean spherical equivalent refractive error and primary open-angle glaucoma (POAG) risk in a cohort from the Genetic Epidemiology Research on Adult Health and Aging consisting of 54,755 non-Hispanic white individuals, of whom 44,344 had refractive error measurements and 4,047 had POAG.
The authors found