What specific risk factors do you discuss with patients who are prescribed GLP-1 agonists?

Recent research has suggested that GLP-1 agonists used to treat obesity might be associated with a stroke in the optic nerve, but association is not the same as causation.
We call a “stroke in the optic nerve” nonarteritic anterior ischemic optic neuropathy (NAION). This is a fancy way of saying lack of blood flow (ie, ischemia) of the front part (ie, anterior) of the optic nerve. The association with GLP-1 agonists could be causal or coincidental because diabetes and obesity, with associated conditions such as hypertension and high cholesterol, are (Read more...)