Macular telangiectasia type 2 is a progressive and relatively rare neurodegenerative disease of the macula that typically affects patients who are older than 40 years of age, more predominantly women.
Initially, macular telangiectasia (MacTel) type 2 was considered a retinal vascular disease; however, over the past decade, studies have revealed that it is in fact a neurodegenerative condition (Kedarisetti and colleagues).
In MacTel type 2, Müller cells, which are important for maintaining the blood-retinal barrier and surround and provide nutrients to retinal neurons, become dysfunctional,