Endophthalmitis Isolates and Antibiotic Susceptibilities: A 10-Year Review of Culture-Proven Cases

We read with great interest the recent article from Schimel and associates on the important topic of antibiotic susceptibility of pathogens isolated in endophthalmitis cases. In particular, we commend the authors for reporting a significant increase in bacterial resistance to fluoroquinolones that might confirm fears concerning the possible loss of an effective therapeutic weapon for the treatment of this potentially blinding disease. A further interesting indication related to the efficacy of vancomycin (100% of gram-positives), confirming the findings of a recent article. However, a 1.5% vancomycin resistance rate has been reported in a further recent large study.

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