Is OCT angiography going to change our lives?

OCT jumped into our lives in 1991 when Huang and colleagues published about a “noninvasive cross-sectional imaging technology in biological systems.” Since then, major advancements have been made. Spectral-domain and swept-source OCT platforms brought faster scans and higher resolution. Also, OCT technology has been proposed in conjunction with adaptive optics, which may allow further resolution, up to a single photoreceptor cell. Polarized light combined with high-resolution OCT scanning may improve characterization of the retinal pigment epithelium. No doubt, therefore, that with the introduction of OCT, assessment of fundus structure has dramatically increased.Amelioration of knowledge on retinal function is also possible thanks to OCT. Functional ultrahigh-resolution OCT may allow the study of retinal response to light stimulation. Quantitative imaging of fundus blood flow and pulsatility of retinal and choroidal vasculature has been proposed with color Doppler OCT.