High genetic risk for AMD may predict benefit from antioxidants

SAN FRANCISCO — Genetic risk and the use of antioxidants play a critical role in the development and progression of age-related macular degeneration, according to a study presented at the American Society of Retina Specialists meeting here.“In persons without AMD, the genetic predisposition to develop AMD can be modified by antioxidant supplements. Antioxidants may be beneficial or detrimental based on individual genetic risk. Persons without AMD and with high genetic risk may benefit from antioxidant supplements. Persons without AMD and with low genetic risk should not take antioxidant supplements,” Carl Awh, MD, said.