Accelerated epi-off cross-linking stabilizes keratoconus

Keratoconus progression was stabilized and vision improved at 2-year follow-up in a study of the safety and efficacy of epithelium-off 15 mW accelerated cross-linking pulsed-light treatment.Several accelerated protocols have been proposed over the years to shorten CXL time and improve patient comfort. At the same time, the role of oxygen for the photochemical activation of riboflavin was proven in several studies, and it was shown that pulsed light might provide better oxygen penetration and diffusion.

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