Author: Healio ophthalmology

EAGLE trial: Lens extraction superior to iridotomy in patients with angle-closure glaucoma

PRAGUE — Lens extraction in angle-closure glaucoma is associated with better clinical outcomes and patient-reported outcomes than laser peripheral iridotomy and appears to be cost-effective, according to the results of the 3-year EAGLE trial.“With 5.3 million people affected worldwide, angle-closure is also a leading cause of blindness. Yet, there is a disproportion in the number of trials as compared with open-angle, and little is known on the efficacy of treatments,” Augusto Azuara-Blanco, MD, PhD, said at the European Glaucoma Society Congress.

Glaucoma drugs may be repurposed with sustained-release implants

PRAGUE — Sustained-release implants may offer the opportunity to repurpose glaucoma drugs, overcoming noncompliance issues, according to one specialist speaking at the European Glaucoma Society Congress. James David Brandt, MD, said that intraocular implants are effective and have the advantage of avoiding allergic reactions on the ocular surface. However, there is a small risk of infection related to the injection, and the procedure is not easily reversible. If the patient develops an adverse reaction such as macular edema, surgery is needed to remove the implant.

Ophthalmoscopy, optic disc photos essential in glaucoma evaluation, management

PRAGUE — Fundus photography remains essential in the diagnosis and follow-up of glaucoma. Imaging cannot capture all signs and should therefore complement but not substitute clinical examination, according to one specialist speaking at the European Glaucoma Society Congress. Thierry Zeyen, MD, PhD, mentioned several studies demonstrating that expert ophthalmologists and optometrists with a special interest in glaucoma were able to assess optic disc photos with equal or even greater precision than HRT, GDx or OCT.

Model of shared care delivery improves glaucoma management at Belgian university clinic

PRAGUE — An innovative model of shared care delivery resulted in optimization of flow, increased patient volume, cost savings and greater satisfaction of patients, employees and glaucoma specialists. Ingeborg Stalmans, MD, PhD, head of the glaucoma unit at Leuven University Hospital, Belgium, talked about this project at the European Glaucoma Society Congress, starting from the observation that optimization of resources might help avoid the two extremes of undertreatment and overtreatment, as well as the problem of capacity saturation in future years.

CHMP recommends change in terms of marketing authorization for Nevanac

The Committee for Medicinal Products for Human Use adopted a positive opinion recommending a change to the terms of the marketing authorization for Nevanac, according to a summary of opinion from the European Medicines Agency. The recommended change is an extended indication that states “Nevanac 3 mg/mL is indicated in adults for prevention and treatment of postoperative pain and inflammation associated with cataract surgery [and] reduction in the risk of preoperative macular edema associated with cataract surgery in diabetic patients,” the opinion said.

Sleeping in lateral decubitus position may cause visual loss in normal-, high-tension glaucoma patients

PRAGUE — Lateral decubitus position during sleeping may be the cause of asymmetric IOP increase and visual field damage in glaucoma patients, according to one specialist speaking at the European Glaucoma Society Congress. IOP increases in the supine position in both healthy and glaucomatous eyes, and studies suggest that this increase might play a role in the progression of glaucoma. Other studies found that in the lateral decubitus position, IOP increases asymmetrically, with higher elevation in the lower eye, Ki Ho Park, MD, PhD, told the audience.