Author: Healio ophthalmology

FDA approves Argus II Retinal Prosthesis System

The Argus II Retinal Prosthesis System from Second Sight Medical Products has been approved by the U.S. Food and Drug Administration.The system, designed to treat adults with advanced retinitis pigmentosa, includes an external small video camera, video processing unit and transmitter fixed to eyeglasses, along with electrodes implanted internally onto the patient’s retina, according to an FDA press release.

Durability of anti-VEGF regimen may increase with low-voltage X-ray irradiation

MIAMI — In previously treated wet age-related macular degeneration, low-voltage X-ray irradiation may increase the durability of a ranibizumab treatment regimen, a speaker said here.In a study led by Darius M. Moshfeghi, MD, 19 patients were given a single treatment of noninvasive, externally delivered low-voltage X-ray irradiation. The 24-Gy dose was administered to patients with neovascular AMD who had been previously treated with intravitreal Lucentis (ranibizumab, Genentech).

New anti-VEGF may improve vision in some patients initially treated with other agents

MIAMI — Some patients currently being treated with bevacizumab or ranibizumab may experience an improvement in visual acuity if their treatment regimen is switched to aflibercept, a speaker said here. Presenting four patient cases, Jason S. Slakter, MD, said Eylea (aflibercept, Regeneron) may create a “marked improvement” in the eye’s anatomy.

Retinal degenerative diseases may be inhibited with tetracyclines

MIAMI — Tetracyclines may inhibit the molecular pathways that contribute to retinal degenerative diseases, specifically retinitis pigmentosa and macular degeneration, a speaker said here.According to Elias Reichel, MD, the TOGA study, a phase 3 study evaluating treatment with Oracea (doxycycline, Galderma) in geographic atrophy, will compare doxycycline with placebo in reducing the rate of change in area of geographic atrophy.

Subretinal injection of human adult stem cells yields favorable results in atrophic AMD

MIAMI — Patients who experience vision loss due to geographic atrophy may respond favorably to a subretinal injection of human adult stem cell therapy, a speaker said here.Allen C. Ho, MD, OSN Retina/Vitreous Board Member, said at Angiogenesis, Exudation, and Degeneration 2013 that stem cell therapy for atrophic age-related macular degeneration holds a promising future in ophthalmology.

CBO lowers estimate for 10-year freeze of payments under the SGR

The Congressional Budget Office recently released its Budget and Economic Outlook: Fiscal Years 2013 to 2023, which lowered the estimate to hold current payment rates under the sustainable growth rate for 10 years from $243.7 billion to $138 billion. “We welcome the news from the [Congressional Budget Office] CBO that the cost of permanently replacing the flawed Medicare physician payment formula, known as [sustainable growth rate] SGR, has decreased dramatically,” AMA President Jeremy A. Lazarus, MD, stated in an AMA press release. “The new cost of freezing payments for 10 years is $138 billion, more than $100 billion less than the previous projection. The rate of Medicare spending growth declined compared to historical trends, and spending for physician services affected by the SGR is projected to be far less than previously estimated.”