CINCINNATI–(BUSINESS WIRE)–Aerpio Therapeutics, Inc., today announced that it has dosed the first subject in a Phase 1a clinical trial evaluating its product candidate AKB-4924 for the treatment of IBD. This novel, orally administered agent that stabilizes hypoxia inducible factor 1 alpha (HIF-1α), a cellular protein which plays a crucial role in the resolution of inflammation and maintenance of epithelial barrier integrity. In multiple in vivo preclinical models of IBD, AKB-4924 has been sho
Corneal transplantation has progressed significantly from full-thickness penetrating keratoplasty to selective corneal transplantation in which only the diseased portions of corneal tissue are replaced surgically with similar healthy donor tissue. This has revolutionized corneal transplantation because the healthy parts of the patient’s cornea are retained. When the endothelium is untouched surgically, this eliminates the possibility of endothelial graft rejection. The diseased portion of the cornea needs to be localized to the anterior regions of the patient’s cornea, such as in keratoconus, while the endothelium remains healthy.When the corneal stroma is (Read more...)
Various innovations in technology and methods have revolutionized ocular surgery by maximizing outcomes and safety, shortening surgical time and reducing stress on patients.Patient comfort and immobility are also critical to surgical success and safety…
(MedPage Today) — Discrepancies between imaging, clinical exam findings
COPENHAGEN – Béatrice Cochener, MD, PhD, president elect of the European Society of Cataract and Refractive Surgeons, talks about management of astigmatism, a key topic in all branches of eye surgery and particularly in cataract surgery. The latest advances in techniques and technology offer unique opportunities to deal effectively with this challenging component of the refractive error.
STAAR Surgical announced the Medical Devices Bureau of Health Canada approved the EVO Visian toric ICL for distribution in Canada. In contrast to traditional contact lenses that are placed on the surface of the eye, the EVO toric ICL is placed inside t…