Intracameral amphotericin B prevents progression of fungal corneal ulcers

Intracameral amphotericin B resulted in faster healing of ulcers and fewer complications than conventional treatment in eyes with fungal keratitis, according to a study.The prospective, nonrandomized study included 104 eyes of 104 patients with fungal corneal ulcers. Forty-nine eyes (group A) responded to conventional topical and systemic antifungal medication and showed signs of healing within 7 days. Fifty-five eyes (group B) did not respond within 7 days and received intracameral amphotericin B in a dose of 5 µg to 10 µg in 1 mL of 5% dextrose.