Joseph Colin, MD, dies of cancer

Joseph Colin, MD, an OSN Europe Edition Board Member, ophthalmic surgeon and educator, died Feb. 24 of metastatic renal cancer. At the time of his death, Colin was the chairman of the Department of Ophthalmology at Bordeaux University Medical School an…

Eylea drives increase in net income for Regeneron

Regeneron Pharmaceuticals reported a net income of $750.3 million in 2012, compared with a net loss of $221.8 million in 2011, according to a company press release.Revenues increased from $445.8 million in 2011 to $1.4 billion in 2012. Eylea (aflibercept) accounted for $838 million in U.S. net sales in 2012, leading to Regeneron’s first full year of profitability, according to the release.

Comparison of Cone Pathologic Changes in Idiopathic Macular Telangiectasia Types 1 and 2 Using Adaptive Optics Scanning Laser Ophthalmoscopy – Corrected Proof

Purpose: To compare pathologic changes in the photoreceptors of eyes with idiopathic macular telangiectasia types 1 and 2 using adaptive optics scanning laser ophthalmoscopy (AO-SLO).Design: Prospective cross-sectional study.Methods: Eleven eyes with idiopathic macular telangiectasia type 1, 14 eyes with type 2, and 10 normal eyes underwent a full ophthalmologic examination, spectral-domain optical coherence tomography (SD-OCT), and imaging with an original prototype AO-SLO system. All eyes with idiopathic macular telangiectasia were examined with fluorescein angiography (FA), confocal blue reflectance, and microperimetry.Results: Compared with normal eyes (29 017 ± 5507 cones/mm2), those with idiopathic macular telangiectasia type 1 had significantly lower cone density (Read more...)

Correlation Between Quantitative Measurements of Tear Film Lipid Layer Thickness and Meibomian Gland Loss in Patients With Obstructive Meibomian Gland Dysfunction and Normal Controls – Corrected Proof

Purpose: To evaluate the correlation between tear film lipid layer thickness and other objective measurements such as tear film break-up time (TBUT), upper and lower meibomian gland losses, and Schirmer 1 test in patients with obstructive meibomian gland dysfunction (MGD) and normal controls.Design: Cross-sectional study.Methods: Thirty eyes of 30 patients with obstructive MGD and 25 eyes of 25 normal controls were enrolled. Lipid layer thickness was measured using an interferometer. Tear film stability and tear production were evaluated by TBUT and Schirmer 1 test. Upper and lower meibomian gland losses were evaluated using noncontact meibography. The correlations among variables were (Read more...)