New cross-linking protocol, device may help fight infectious keratitis on a global scale

LISBON, Portugal — An optimized treatment protocol, a miniaturized device that mounts on a slit lamp and a new photosensitizing agent may allow for a faster and more effective application of cross-linking for infectious keratitis in the near future. Cross-linking for infectious keratitis, now called PACK-CXL for photoactivated chromophore for keratitis-CXL, disinfects the corneal surface via reactive oxygen species and increases the resistance to enzymatic digestion by modification of the collagen structure.

Cost, accessibility remain issues for homebased monitoring of AMD

LISBON, Portugal — Daily home-based monitoring of age-related macular degeneration can have a positive impact on prompt, early treatment and preservation of vision, but access and cost may be issues, speakers said during a debate at the Controversies in Ophthalmology meeting. Susan B. Bressler, MD, PhD, presented results of the National Eye Institute’s HOME study, a secondary study to AREDS2, in which the ForeseeHome AMD Monitoring Program (Notal Vision) was used. The study was a 3-year phase 3 trial in which 1,520 participants were randomized 1:1 into the device group (Read more...)

Under-monitoring, under-treatment of AMD confirmed by real-life studies

LISBON, Portugal — Real-life studies carried out in different countries confirmed that age-related macular degeneration patients who require intravitreal anti-VEGF injections are under-monitored and under-treated. “Several studies already published, including LUMIERE, AURA, WAVE and Coimbra, as well as Medicare data, seem to indicate that this is the scenario all over the world,” Rufino Silva, MD, said at the Controversies in Ophthalmology meeting. The studies looked at the results of real-world clinical practice and revealed a scenario that is different from what should be expected by following the recommendations of clinical (Read more...)