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MIAMI — Geographic atrophy is part of the overall age-related macular degeneration disease process and was seen in more than half of eyes with wet AMD in one study, a speaker said here. “It’s not a different disease — it’s part of the disease,” Jason S. Slakter, MD, said at the Angiogenesis, Exudation, and Degeneration 2014 meeting. “We all know that CNV develops in patients with dry AMD — we’ve known that for years — but everyone is kind of shocked that we might get geographic atrophy in patients with (Read more...)

MIAMI — A new generation of antioxidants under pharmaceutical development is intended for the treatment of age-related macular degeneration in manufactured doses greater than what can be obtained over the counter, a speaker said here. In models in which “megadoses” of vitamin E were used, drusen formation was hindered, but the doses would have been toxic in humans, Scott W. Cousins, MD, said at the Angiogenesis, Exudation, and Degeneration 2014 meeting. “It’s not that the antioxidant mechanism of action is wrong; it’s that the nutraceutical is not performing the way (Read more...)

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