Tag: Genetics

Engineering Immune Organoids : An Interview with Prof. Ankur Singh from Cornell University

Organ-on-a-chip technologies are redefining the way in which in vitro models help understand and recapitulate the in vivo environment. The immune system is particularly difficult to model in an in vitro environment because of the complexity of biological, mechanical, and chemical cues that modulate the immune cells. Prof. Ankur Singh, an assistant (Read more...)

Magnets and Nanoparticles for On-Demand Leaky Vessels

Scientists at Rice University have developed a method to open gaps between the endothelial cells that line blood vessels using a magnetic field and iron oxide nanoparticles. The gaps close by themselves after the researchers remove the magnets. They hope that the concept could be used to help deliver larger therapeutic molecules like proteins to [& (Read more...)

Diagnosing Multiple Sclerosis with a Blood Test: Interview with IQuity CEO, Dr. Chase Spurlock

Multiple sclerosis (MS) is an autoimmune disease that afflicts an approximate 2.5 million patients world-wide, giving rise to multiple issues regarding quality of life and the potential for disability. Up to 15,000 people are newly diagnosed with MS every year in the US, while another 45,000 experience a clinical precursor with similar symptom (Read more...)

Microchip Sorts DNA Fragments by Size in Minutes

At the University of Twente in The Netherlands, scientists have come up with a rapid and inexpensive way of separating out DNA fragments from a sample. The technology will help speed up DNA sequencing, which normally relies on using computers to virtually combine millions of DNA fragments into a single string. Currently, the so-called fraction (Read more...)

23andMe: A Medgadget Review

In 2007, Anne Wojcicki’s 23andMe transformed personalized health with the unveiling of a direct to consumer genetic testing service in which subscribers would receive information about their ancestry, physical traits, and disease carriers by simply providing a saliva sample via mail to the company’s labs. Since then, 23andMe h (Read more...)

Laser Treated Graphene Circuits Push Stem Cells to Differentiate Into Neural Schwann Cells

Schwann cells are important targets for stem cell therapy because they surround neural axons and can help regrow damaged or diseased nerves, potentially restoring movement to disabled arms and legs. Differentiating such cells has been difficult, but researchers at Iowa State University may have stumbled on a technique that will allow for mass produ (Read more...)

Stretching Cells with Laser Pulses

The establishment of cell culture systems opened the door to an unparalleled revolution in biomedical science, but this common lab practice remains drastically artificial and is often not translatable to real-life in vivo systems. This limitation is particularly notable in efforts aiming to understand the mechanisms regulating responses of cells an (Read more...)

Light Used to Activate Select Proteins Inside Living Cells

At the University of Alberta in Canada, researchers have devised a way of activating proteins inside a living cell using a beam of light. This will allow scientists to study how the activation of certain proteins affects the functionality of a cell. The technological breakthrough consists of attaching a photocleavable protein, one that can be (Read more...)

Tiny Paper Pumps to Power Microfluidic Devices

Microfluidic technology promises to make a lot of medical tests, that are currently expensive and difficult to perform, a lot cheaper, easier, and more portable. While there’s been a tremendous amount of progress in this field, challenges remain. One is that microfluidic devices coming out of labs are often powered by much larger, external pu (Read more...)