Tag: Genetics

New Technique for Cheaper, More Efficient Single Cell Sequencing

by Medgadged • 2017/02/23 • 0 Comments

Single-cell sequencing has shown a lot of promise in identifying genetic differences between cells in a given tissue sample. It is particularly useful for understanding heterogeneity and evolution in resected tumors, and is increasingly used for improving precision medicine approaches. Unfortunately, conventional methods are cost-prohibitive, thus they restrict the cell numbers that can be assessed […]

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DNA Computer Can Sense Multiple Antibody Inputs, With Potential for Smart Drug Delivery

by Medgadged • 2017/02/21 • 0 Comments

Researchers at the University of Eindhoven in the Netherlands have developed a DNA computer that can respond to the presence of specific antibodies and make calculations, with the potential for intelligent drug delivery in the future. DNA computing involves using DNA molecules and other molecular biological components as molecular circuitry, instead of traditional silicon-based circuitry […]

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Novel Material Made of Living Cells Glows When Touching Certain Chemical Compounds

by Medgadged • 2017/02/17 • 0 Comments

Scientists at MIT have developed a unique material that contains living, genetically engineered cells that fluoresce in the presence of specific chemicals. So far the potential of the technology has been demonstrated in gloves and bandages that light up when a certain compound is present in the exudate they come in contact with. The material […]

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Synchronized 3D Beating Heart Tissue Made from Multiple Cell Types

by Medgadged • 2017/02/17 • 0 Comments

At the York University in Toronto, Canada researchers have come up with a way of integrating three different cardiac cell types into a single functional, 3D beating tissue. Unlike many other tissue engineering techniques, the York team didn’t use any scaffolding to hold the cells in place. The cells, which were contractile myocardial cells, connective tissue […]

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Revolutionary New Technique Visualizes Biomolecules Without Crystallization

by Medgadged • 2017/02/16 • 0 Comments

In the latest issue of Proceedings of the National Academy of Sciences, researchers from MIT and Singapore University of Technology and Design are describing a new technique that may finally give life scientists a detailed view into many of the biomolecules they work with. These days, X-ray diffraction is typically used to see the structure of […]

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Adaptive Liquid Lenses and Smartphones Shrink Digital Pathology Into a Tiny Portable Device

by Medgadged • 2017/02/15 • 0 Comments

At Ohio State University researchers have developed a portable pathology slide scanner that uses a smartphone to image, display, and share the scans. Unlike conventional microscopy, digital pathology devices image the entire slide and therefore provide a much wider field of view. This makes it easier to identify tissues that may be a and indicator […]

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Nanoparticles Deliver CRISPR/Cas9 Genetic Editor Safely Into Cells

by Medgadged • 2017/02/14 • 0 Comments

CRISPR/Cas9, a powerful gene editing technique that has already been used in a human, is thought by many as a “cut and paste” for DNA in living organisms. While in a sense that is what happens, delivering the ribonucleoprotein that does the genetic editing and the RNA that hones in on the target, into the cellular […]

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Cheap Method for Printing Lab-on-Chip Devices Promises Diagnostic Revolution

by Medgadged • 2017/02/09 • 0 Comments

Scientists at Stanford University have developed a new method of manufacturing lab-on-chip devices that cost only pennies to make, which can be used for research and point-of-care diagnostics, particularly in poorer places around the world. The investigators built such devices and showed that they can be used to separate cells from a sample, isolate target […]

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SkinGun Investigational Therapy for Burns Uses Patients’ Own Stem Cells for Healing

by Medgadged • 2017/02/02 • 0 Comments

RenovaCare, a company based in New York City, is seeking FDA approval for the SkinGun, a device to treat burns using a patient’s own stem cells. Significant portions of skin can be destroyed in burn injuries, meaning that regenerative therapy is required to restore or replace the injured tissue. Current treatments for burns involve skin grafting, […]

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PerkinElmer’s New Vectra Polaris Automated Quantitative Pathology System for Studying Cancer Immunotherapies

by Medgadged • 2017/02/02 • 0 Comments

PerkinElmer is releasing a new automated quantitative pathology system, the Vectra Polaris. It was developed to help study how cancer immunotherapies are affecting their targets and nearby tissues. The machine is able to detect multiple immunohistochemical stains simultaneously thanks to multispectral imaging using seven colors, allowing for more complicated studies that identify interesting correlations. The slides […]

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New gene-editing technology partially restores vision in blind animals

by Medical News Today • 2016/11/18 • 0 Comments

Salk Institute researchers have discovered a holy grail of gene editing – the ability to, for the first time, insert DNA at a target location into the non-dividing cells that make up the majority…

First small molecule targeted therapy to mitigate hearing loss in Usher syndrome type 3

by Medical News Today • 2016/04/28 • 0 Comments

Usher syndrome (USH) is characterized by hearing loss or deafness at birth and progressive vision loss, and is the most common cause of inherited dual sensory deficit.

Light Used as Pacemaker to Set Rhythm of Beating Heart

by Medgadged • 2015/08/04 • 0 Comments

There must have been one or two love songs that predicted optogenetic cardiac pacing with words like “you are the light that makes my heart beat.” Now the idea has literally come true thanks to researchers at Israel’s Technion-Institute of Technology who were able to use light pulses in a manner of a cardiac pacemaker to […]

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Light Used as Pacemaker to Set Rhythm of Beating Heart

by Medgadged • 2015/08/04 • 0 Comments

The post Light Used as Pacemaker to Set Rhythm of Beating Heart appeared first on Medgadget.

Diseases result from gene mutations linked to a molecular motor responsible for human development

by Medical News Today • 2014/09/12 • 0 Comments

Another mystery of the human body has been solved by scientists who have identified how a molecular motor essential for human development works.

Discovery of gene may lead to therapy for a retinal disease

by Medical News Today • 2013/09/11 • 0 Comments

Newly-reported findings by researchers at Michigan State University (MSU) provide the first phenotypic evidence that a mutated gene causes one form of progressive retinal atrophy in papillon dogs. Progressive retinal atrophy is analogous to one of the …

Using Lipid Nanoparticles To Deliver Genes And Drugs

by Medical News Today • 2013/03/04 • 0 Comments

At the Faculty of Pharmacy of the Basque Public University (UPV/EHU) the Pharmacokinetics, Nanotechnology and Gene Therapy research team is using nanotechnology to develop new formulations that can be applied to drugs and gene therapy…

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