Tag: Materials

Cooling Vest Helps COVID Clinicians with Heat Stress

Researchers from the Radboud University Medical Center in The Netherlands have trialed cooling vests, originally designed for elite athletes, in nursing staff who have to put in long shifts in COVID-19 wards wearing full personal protective equipment (PPE). While essential, the protective equipment can lead to significant discomfort in the form of heat stress. The […]

10 Second COVID Antibody Test on a Chip

Researchers at Carnegie Mellon University have developed a microfluidic chip that can provide rapid COVID-19 antibody tests. The electrochemical test can detect very low concentrations of antibodies in blood samples, and transmits the results to a smartphone. The test could help to measure patient responses to vaccines and determine if they have been previously exposed […]

3D Imaging Illuminates Internal Structure of Brain Spheroids

Researchers at the Wyss Center in Geneva and collaborators have developed novel imaging and labeling techniques to view the internal structure of brain spheroids, and observe the morphology of single neurons in 3D. Brain spheroids, which the researchers term “mini brains,” are a cluster of different types of brain cells, and are cultured from induced […]

Magnetic Nanoparticles Deliver Chem and Heat Cancer Cells for Synergistic Effects

Researchers at University College London have shown that tiny magnetic nanoparticles could enhance cancer treatment. The particles can deliver chemotherapy drugs to cancer cells and also produce a mild heating effect when stimulated with an external alternating magnetic field. Combining particle-mediated heat treatment and chemotherapy resulted in synergistic effects in killing cancer cells, suggesting that […]

Sensor Converts Forearm Signals to Control Prosthetic Hands

Researchers at the University of California, Berkeley have developed a wearable sensor that can measure electrical signals in the forearm and use AI to correlate them with hand gestures, such as the movements of individual fingers. The team demonstrated that the system can control a robotic prosthetic hand and that it may provide a way […]

Artificial Attachments for Immune Cells Help Kill Tumors

Though immune cells have the capabilities to kill cancer cells, they’re often thwarted by cancer’s ability to evade detection. Researchers at Pennsylvania State University have now developed engineered natural killer cells that have a much better ability to find and kill cancerous cells. “We explored a novel method to engineer natural killer cells,” said Yong […]

Radiotherapy to Prevent Recurrence Post Brain Tumor Excision: Interview with Matthew Likens, President and CEO of GT Medical

GT Medical Technologies, a company based in Arizona, has developed the FDA-approved GammaTile system, which can provide localized radiation therapy for brain tumor excision sites. Its goal is to reduce tumor recurrence and enhance patient survival. The treatment consists of radiation seeds encased in a collagen substrate. These are easy to place at the excision […]

Microbubbles Deliver Drugs Directly to Tumors

When fighting cancerous tumors, all too often the very drugs that can destroy a lesion tend to have significant negative effects on the rest of the body. Doses have to be maintained at moderate levels to avoid side-effects that are even worse than the disease. In light of this, researchers have been trying to develop […]

Interlocking Metals and Polymers for Magnetically Controllable Therapeutic Microrobots

Researchers at ETH Zurich have developed a technique to create tiny microrobots with interlocking polymer and metal parts that can be controlled using magnetic fields. The magnetic metal components can move within the polymer frame, providing locomotion, and the tiny bots are small enough to traverse blood vessels, potentially functioning as vehicles to deliver drugs […]

Hydrogel Contact Lens Measures Biomarkers in Tears

Researchers at the Terasaki Institute in Los Angeles have developed a prototype of a contact lens that can assist with tear sampling for diagnostic purposes, and to also improve tear flow to potentially prevent dry eye disease. The hydrogel lens contains microchannels through which tears can travel and testing chambers where electrochemical and colorimetric tests […]

Highly Realistic 3D Printed Human Hearts

Physical models of organs and tissues have many uses in clinical medicine, particularly when preparing for challenging surgeries. Naturally, the heart is commonly modeled using 3D printing to most closely mimic the nuances of unique patient anatomies. This is useful when preparing for procedures such as mitral valve repairs, but typically this is accomplished using […]

Red Blood Cells Deliver Nanoparticles to Provoke Immune Response to Lung Metastases

Researchers at Harvard’s Wyss Institute have developed a way to deliver immune-stimulating agents to lung metastases. Their system involves nanoparticles loaded with an immune-stimulating agent that are attached to red blood cells. When injected into the blood stream, the red blood cells shed the nanoparticles as they squeeze through the narrow capillaries of the lungs, […]

Stretchable Fiber-Optic Sensors for Skin-Like Sensation

Researchers at Cornell University have developed stretchable sensors that can detect sensations such as strain, pressure, and bending, much like human skin. Deformation is measured through changes in optical paths within the flexible fiber optic sensors. By providing a sense of ‘touch’, the sensors could provide additional functionality for medical soft robots or prostheses and […]

Elastomeric Respirator Mask Senses Fit and Filter Saturation

Researchers at Brigham and Women’s Hospital and Massachusetts Institute of Technology have designed a new respirator, conceived as an improvement on standard N95 masks. The transparent respirator contains sensors that allow users to know if the mask is fitting snugly and alerts them when the filters need to be replaced. The mask, called the transparent, […]

Flexible Patch Monitors and Treats the Beating Heart

Researchers at the University of Houston and colleagues have developed a flexible epicardial patch which can monitor heart function and even administer treatments, such as thermal ablation and heart pacing. The device can harvest power directly from the movement of the beating heart and its flexibility means that it conforms well with the epicardial surface, […]

Microfluidic Device to Test Pancreatic Cancer Drugs

Certain varieties of pancreatic cancer exhibit multiple tumor cell subtypes that work, somewhat mysteriously, to quickly become resistant to chemotherapy agents. Researchers at Purdue University have now built a unique microfluidic device that can be used to test a cancer drug on multiple tumor cells subtypes. Using this technology the researchers believe that new drug […]

Octopus-Inspired Sucker for Tranplanting Cell Sheets

Researchers at the University of Illinois have developed a ‘sucker’ to pick up and transfer thin cell or tissue sheets that are intended for therapeutic purposes, such as wound healing or tissue grafting. Inspired by octopus suckers, the device can gently manipulate the delicate sheets without causing damage, and uses heating and a temperature-responsive hydrogel […]

Supportive Gel Allows for Bioprinting of Complex Shapes

Researchers at Penn State have developed a supportive gel that allows for printing of complex shapes using cell aggregates. The gel provides a supportive matrix during the printing process, and permits the researchers to place the aggregates wherever they want. This technique could pave the way for printed replacements for tissues and organs. Bioprinting, where […]

Tiny Robots Walk Through Colon to Deliver Drugs, Sample Tissue

Delivering drugs to internal organs and tissues is usually achieved through ingested medications, but these are often diluted and intercepted before enough can reach the intended destination. Targeted delivery is preferred but usually very difficult to accomplish, particularly when there’s a lot of fluids and movement. This is the case with the colon, an organ […]