Researchers at Harvard’s Wyss Institute have modeled Environmental Enteric Dysfunction (EED), a childhood inflammatory intestinal disease, on a microfluidic chip and gained new insights into the genetic changes underlying the condition. This is the first in vitro model of the disease, and highlights the power of organ on a chip systems to pro (Read more...)
Tag: Materials
One-Step Manufactured Meta-Bots with Medical Potential
Engineers at the University of California Los Angeles have developed “meta-bots,” which are fingernail sized robots that can move, sense, and navigate their environment. Strikingly, the robots are essentially ready for use when they emerge from the 3D printer, and consist of piezoelectric actuators that can respond to or generate electr (Read more...)
Polymer Brushes Capture and Release Proteins on Demand
Researchers at the Chalmers University of Technology in Sweden have developed a “polymer brush” system that can capture and release proteins on using electrical stimulation. Protein therapeutics are increasingly in demand, but creating them efficiently is still a challenge. Isolating therapeutic proteins from the liquid surrounding the (Read more...)
Self-Regulating Footwear for Diabetic Foot Issues
Researchers at the Indian Institute of Science created footwear that can self-regulate the pressure distribution when a person walks, helping to avoid pain and friction that can lead to issues for people with diabetes. Patients with diabetes can have an abnormal gait, sometimes because of pain or numbness in the extremities, potentially leading to (Read more...)
Living Skin Layer for Robots and Prostheses
Researchers at the University of Tokyo have developed a method to coat a robotic finger in a living “skin” layer. The living coating is strong and flexible enough to allow the robotic finger to bend and flex, and it can repel water and even self-heal if damaged. The technique involves coating the robot in a […]
Fabric Makes Electricity from Movement to Power Wearables
Scientists at Nanyang Technological University, Singapore, have created a wearable fabric that generates electricity from our body movements. The fabric could assist in powering medical wearables and other mobile diagnostic or therapeutic devices. The fabric contains stretchable polymers that generate electricity when bent, pressed, or brushed, bas (Read more...)
Melt Electrowriting to Make Fibrous Heart Valve Scaffolds
Researchers at the Technical University of Munich in Germany have developed a technique to create heart valve scaffolds that can mimic the variable mechanical properties of the real thing. The researchers used a method called melt electrowriting to create complex and variable patterns in the fibrous scaffolds, allowing them to mimic the structure a (Read more...)
Photonic Technique for Deeper Fluorescent Sensors
Researchers at MIT have developed a method that lets them read the signal from fluorescent sensors that are as deep as 5.5 centimeters in tissue. Previously, it was very difficult to get a good signal from a fluorescent sensor placed that deep, as fluorescence emitted by the tissue itself would muddy the signal. The new […]
Dissolving Pacemaker Communicates with Patient and Wearable Tech
Researchers at Northwestern University have created a cardiac pacemaker that dissolves away, negating the need for a procedure to remove it. The pacemaker was originally announced in 2021, but in this follow-up study, the researchers have enhanced its functionality. The device can now communicate with a network of wireless sensors that are worn on (Read more...)
Thin Film Electrodes for Neuro Applications: Interview with Dave Rosa, CEO of NeuroOne
NeuroOne, a medtech company based in Minnesota, has developed the Evo Cortical Electrode and the sEEG electrode, both of which are thin film electrodes for neural recording and stimulation. The small profile and flexible nature of the electrodes allows for less invasive insertion, and the low resistance they offer delivers improved signal quality. (Read more...)
Tiny Robot Crab to Perform Tasks Inside Body
Engineers at Northwestern University have developed a tiny remote controlled crab robot. The device is just half a millimeter wide, and can perform a variety of impressive tasks, including jumping, twisting, bending, turning, and walking. The tiny devices do not require electricity and instead are powered through heating using a laser. The shape-me (Read more...)
Artificial Skin Senses Pressure, Temperature, Humidity
Researchers at Graz University in Austria have created an artificial skin that is more sensitive than your fingertip. The skin contains 2,000 sensors per square millimeter, and the researchers designed it to sense humidity, temperature, and pressure, just like human skin. The tiny sensors within the skin material consist of a hydrogel core and a [& (Read more...)
New Antimicrobial Surface for Implantable Devices
Researchers at the University of California Los Angeles have created a zwitterion polymer coating for in-dwelling medical devices, such as urinary catheters, that prevents microbes from adhering and creating troublesome biofilms. Recurrent infection and biofouling are a serious problem for such devices, leading to the overuse of antibiotics and the (Read more...)
Glucose Fuel Cell to Power Medical Implants
Scientists at MIT created a glucose fuel cell that is small and powerful enough to conceivably power medical implants using the sugar present in our blood. The ultrathin device relies on a ceramic material as an electrolyte and platinum anodes/cathodes. The researchers were able to place just over 150 fuel cells onto a chip and […]
Wearable Uses Microneedles to Track Metabolism
A team of researchers at the University of California San Diego created a wearable device that uses a disposable microneedle patch to continuously sample and analyze interstitial fluid. The wearable can measure glucose, alcohol, and lactate levels, all of which could be useful information for patients with diabetes. The disposable patch is attached (Read more...)
Advanced Multi-Organ Chip for Personalized Medicine
Researchers at Columbia University School of Engineering and Applied Science developed an advanced organ-on-a-chip system that incorporates heart, bone, liver, and skin tissue in independent niches that are linked with simulated vascular flows. The system even includes immune cells that circulate within the simulated vasculature. The technology rep (Read more...)
Soft Robotic Sleeve for Lymphedema Treatment
Researchers at the University of Waterloo in Canada created a soft robotic sleeve to treat lymphedema. Lymphedema involves fluid accumulation in tissues because of damage to the lymph system. This wearable sleeve combines a microfluidic controller and soft robotic components that apply compression to the arm to reduce and control fluid accumulation (Read more...)
Heart Chamber on a Chip
Researchers at Boston University engineered a heart chamber on a chip that can beat by itself. The technology relies on cardiomyocytes generated from induced pluripotent stem cells and small acrylic valves that allow the fluid pumped by the chamber to come and go. The chamber is supported by a thin acrylic scaffold that aims to […]
Printing Bone Constructs During Surgery
Scientists at Penn State developed a method to print a ‘bone’ construct during a surgical procedure. The technique is intended to allow surgeons to rapidly fill bony defects that would not easily heal by themselves, and the researchers have turbo-charged the technique by including genes that promote bone formation. Consequently, they de (Read more...)
Printed Fingertip with Enhanced Tactile Sense
Researchers at the University of Bristol in the UK have created a 3D printed fingertip that is designed for use by robots or as a component of robotic prostheses. The structure mimics the dermal papillae found in human skin, which are small bumps present between the dermis and epidermis that are important in human touch. […]
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