Researchers at MIT have developed an enhanced mRNA vaccine system that can elicit a greater immune response at lower doses. The vaccine technology is so potent that it may be useful for intranasal COVID-19 vaccines. This would have the benefit of localized immunity in the nasal mucus membranes that could kill the SARS-CoV-2 virus before […]
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Enhanced mRNA Vaccine May Work Intranasally.
Researchers at MIT have developed an enhanced mRNA vaccine system that can elicit a greater immune response at lower doses. The vaccine technology is so potent that it may be useful for intranasal COVID-19 vaccines. This would have the benefit of localized immunity in the nasal mucus membranes that could kill the SARS-CoV-2 virus before […]
Soft Implant Uses AI to Deliver Drugs Despite Fibrous Encapsulation
Scientists at the University of Galway in Ireland and MIT have collaborated to create a soft robotic implant that can work to fight fibrotic encapsulation and deliver drugs despite the presence of fibrous scar tissue. The device, which the researchers have termed the FibroSensing Dynamic Soft Reservoir (FSDSR), is designed to reside in the body […]
Conductive Polymer Electrode is Metal-Free
Researchers at MIT have developed a metal-free electrode using conductive polymers. The electrode is flexible and strong enough for long-term implantation in the body. The device is intended as an advanced replacement for rigid metal electrodes that can cause tissue damage and scarring over the long term, leading to device failure. The new technology required […]
Patient-Specific Soft Robotic Heart Replicas for Treatment Planning
Researchers at MIT have developed soft robotic heart replicas that closely match the anatomy of real people. The researchers used medical images of patient hearts to construct computer models that are suitable for 3D printing. Once printed with a soft material, the patient-specific heart models can be actuated using external inflatable sleeves, in the style […]
Ingestible Sensor Reveals Gastric Motility
Researchers at MIT have developed an ingestible sensor that can reveal gastrointestinal motility issues, such as gastroparesis and gastroesophageal reflux disease. The technology is intended for use as an easy at-home method to diagnose such issues, which typically require more invasive and inconvenient procedures, such as endoscopy or X-ray imaging. This new technology is based […]
Implanted Magnets for Prosthetic Control
Engineers at MIT have developed a system that could let users of robotic prostheses to more sensitively control their bionic limbs. The technology involves implanting pairs of small magnetic beads into muscles. When the muscles contract, the beads move closer together, allowing prosthetic devices to more precisely calculate a user’s intentions and mirror these. Current […]
Flexible Sensors Measure Fit of Face Masks
Researchers at MIT have developed a sensor system that can provide data on how well a face mask fits to a wearer’s face. The protection offered by a mask is largely dependent on how well it fits the face, but at present most face masks are one-size-fits-all and most wearers are largely unaware if their […]
Robotic Capsule Drills Intestinal Mucus to Deliver Protein Drugs
Engineers at MIT have collaborated to develop a robotic drug delivery capsule that is specially designed to administer delicate protein drugs, such as insulin, through the wall of the intestine. Proteins are not suited for oral delivery, as they are typically destroyed by the low pH in the intestine and they can’t pass through the […]
AI Device Monitors Breathing to Diagnose Parkinson’s
Researchers at MIT have developed an AI system that can diagnose Parkinson’s disease and track its progression, simply by monitoring someone’s breathing patterns as they sleep. The device looks like an internet router and can be mounted on the wall in a bedroom. It emits radio waves and then a neural network analyzes the reflected […]
Ultrasound Sticker for 48 Hours of Imaging
Engineers at MIT have created an ultrasound patch that can provide long-term ultrasound imaging of internal organs and structures. The device contains a rigid piezoelectric probe array and uses an underlying layer of elastomer-covered hydrogel in lieu of the gel applied to the skin during conventional ultrasound procedures. At just the size of a postage […]
Microparticle Vaccine Provides Boosters Automatically
Researchers at MIT have created a microparticle vaccine that can provide booster doses automatically. The hollow microparticles resemble a coffee cup with a lid, and are made using poly(lactic-co-glycolic acid), otherwise known as PLGA. The polymer breaks down over time in the body, releasing the contents of the hollow particles. By changing the composition of […]
Smart Textiles Recognize Body Movements
Engineers at MIT have developed smart textiles that can detect and recognize body movements. The garments fit snugly, and contain a network of pressure sensors that can detect movement, and in conjunction with machine learning approaches, the technology can learn to recognize specific movements in wearers. The fabric contains conductive yarns and piezoresistive components that […]
Photonic Technique for Deeper Fluorescent Sensors
Researchers at MIT have developed a method that lets them read the signal from fluorescent sensors that are as deep as 5.5 centimeters in tissue. Previously, it was very difficult to get a good signal from a fluorescent sensor placed that deep, as fluorescence emitted by the tissue itself would muddy the signal. The new […]
Glucose Fuel Cell to Power Medical Implants
Scientists at MIT created a glucose fuel cell that is small and powerful enough to conceivably power medical implants using the sugar present in our blood. The ultrathin device relies on a ceramic material as an electrolyte and platinum anodes/cathodes. The researchers were able to place just over 150 fuel cells onto a chip and […]
Telerobotic System Uses Magnets to Perform Endovascular Procedures
Researchers at MIT have developed a telerobotic surgical system that allows a surgeon to remotely treat patients who are suffering a stroke or aneurysm. The system could be very useful, as achieving treatment as soon as possible after a stroke is crucial, but the endovascular surgeons who specialize in treating such patients may not be […]
New System Speeds Up Typing for the Motor Impaired
Researchers at MIT have created a new text selection interface for motor impaired individuals. People with severe physical disabilities can type to communicate with others, and often activate a switch or blink an eye to indicate a letter selection in a grid of letters on a computer screen. This approach to typing is painstaking and […]
Acoustic Fabric Listens to Heart and Breathing, Works as Hearing Aid
Researchers at MIT have created an “acoustic fabric” that can listen to its surroundings and convert the vibrations made by sound into electrical signals, much like the human ear or a microphone. The technology consists of piezoelectric fibers that are woven into the fabric, and the resulting machine-washable material could prove useful for a variety […]
Surgical Duct Tape Quickly Seals Intestinal Leaks
Researchers at MIT have created a surgical tape that can seal leaks and tears in the intestine. The off-the-shelf product has been designed to replace sutures, which are difficult to sew in the gut and can cause scarring or leaking. The adhesive patch is biocompatible, and the researchers designed it so that it will biodegrade […]
Capsule Delivers and Injects mRNA into Stomach
Researchers at MIT have created an oral mRNA delivery system that could provide an alternative to injectable mRNA vaccines. It could also enable RNA or DNA therapies that are intended to treat gastrointestinal diseases. mRNA has shown its therapeutic potential in spectacular fashion, providing the powerhouse behind some of the world’s most successful and ubiquitous […]