News Cerebrospinal Fluid Antibodies to Aquaporin-4 in Neuromyelitis Optica and Related Disorders: Frequency, Origin, and Diagnostic Relevance by Medscape • 2010/11/17 • 0 Comments Evidence suggests that serum antibodies to aquaporin-4 are directly involved in the pathogenesis of neuromyelitis optica. How diagnostically relevant is its presence in cerebrospinal fluid? Journal of Neuroinflammation Full Story →