Cost-Effectiveness of Descemet’s Stripping Endothelial Keratoplasty versus Penetrating Keratoplasty

Purpose: Selective endothelial transplantation in the form of Descemet's stripping endothelial keratoplasty (DSEK) is rapidly replacing traditional full-thickness penetrating keratoplasty (PK) for endothelial disease. An incremental cost-effectiveness analysis was performed to determine whether the benefits of DSEK are worth the additional costs. Design: Retrospective cohort study. Participants: Patients at the Singapore National Eye Center, a tertiary eye center in Singapore, with Fuchs' dystrophy or bullous keratopathy who underwent either PK or DSEK. Intervention: Patients underwent either PK (n = 171) or DSEK (n = 93) from January 2001 through December (Read more...)

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