The Incidence of Acute Anterior Uveitis after Intravenous Zoledronate

Purpose: To investigate the incidence of significant adverse ocular side effects after intravenous zoledronate infusion for osteopenia. Design: Data analysis of a large, prospective, randomized, double-blind, placebo-controlled clinical trial. Participants: Postmenopausal women (n = 2001) with osteopenia randomized to placebo or zoledronate infusion. Intervention: Intravenous infusion of zoledronate 5 mg or placebo. Main Outcome Measures: Adverse ocular events. Results: Eight participants (mean age, 70.4±5.3 years) with uniocular or bilateral painful red eye were diagnosed with acute anterior uveitis (AAU) after examination by an ophthalmologist. All cases of AAU were from (Read more...)

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