The Incidence of Acute Anterior Uveitis after Intravenous Zoledronate
Purpose:
To investigate the incidence of significant adverse ocular side effects after intravenous zoledronate infusion for osteopenia.
Design:
Data analysis of a large, prospective, randomized, double-blind, placebo-controlled clinical trial.
Participants:
Postmenopausal women (n = 2001) with osteopenia randomized to placebo or zoledronate infusion.
Intervention:
Intravenous infusion of zoledronate 5 mg or placebo.
Main Outcome Measures:
Adverse ocular events.
Results:
Eight participants (mean age, 70.4±5.3 years) with uniocular or bilateral painful red eye were diagnosed with acute anterior uveitis (AAU) after examination by an ophthalmologist. All cases of AAU were from (Read more...)