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Rheumatoid factor, antinuclear antibody may portend primary Sjögren’s syndrome
Specific diagnostic testing protocols may show signs of Sjögren’s syndrome in patients with clinically significant dry eye, according to a study.The prospective multicenter study included 327 patients with clinically significant aqueous-deficient dry eye. Investigators conducted Schirmer testing, corneal fluorescein staining, conjunctival lissamine green staining and tear film breakup assessment. Patients also took a questionnaire on their history of systemic disease and dry eye.