Characteristics of Immune Rejection after Allogeneic Cultivated Limbal Epithelial Transplantation

Purpose: To investigate the characteristics and prognosis of immune rejection after allogeneic cultivated limbal epithelial transplantation (CLET). Design: Retrospective, noncomparative case series. Participants: Forty-two eyes of 41 patients undergoing allogeneic CLET for total limbal stem cell deficiency who completed a follow-up of at least 12 months. Methods: Allogeneic cultivated limbal epithelial cells using human amniotic membrane as a carrier were transplanted into the recipient eye. Immune rejection occurred in 10 eyes; the medical records of these patients were reviewed. Main Outcome Measures: Best-corrected visual acuity, corneal opacification and neovascularization, immunofluorescence (Read more...)

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