Visual Outcome After Antioxidant Supplementation

In 2001, the National Eye Institute–funded Age-related Eye Disease Study (AREDS) published its findings. The AREDS was a double-masked, randomized, placebo-controlled trial of 4757 subjects over a period of 5 years that showed that supplementation with antioxidants vitamins C and E, β-carotene, and zinc in combination resulted in a 25% relative reduction in the risk of progression from intermediate to advanced and visually consequential age-related macular degeneration (AMD). The AREDS supplement did not contain the macular pigment carotenoids lutein and zeaxanthin, compounds believed to confer protection against development and/or progression (Read more...)

Full Story →